This expert review sums up research on ADHD in children, teenagers and adults. It has no sample of its own.
The authors describe ADHD as common and mostly genetic. About 5.3% of school-aged children have it. Two-thirds of children with ADHD still have impairing symptoms as adults, at full or milder levels. Children with ADHD were more likely to have conduct problems, depression and anxiety.
The review says diagnosis is reliable when done with standard criteria through a clinical interview. No test or scan is accurate enough to diagnose ADHD on its own. There is no cure. Medicines are effective for core symptoms and are usually well tolerated. Behavioral therapy helped children's behavior and their parents' skills, though one figure in the review calls its evidence for core symptoms less consistent. In adults, talk therapy (CBT) helped anxiety, depression, self-esteem and emotional control. It did not cut core symptoms as much as stimulant medicine.
The authors note limits. Most genetic studies used people of European ancestry. No one can yet predict who will respond to a treatment.
The authors suggest that clinicians diagnose ADHD through a clinical interview, never a checklist alone, and reassess treatment at least once a year.
Talk to a clinician about your own situation.
The numbers Stats and what the terms mean
The statistics behind the plain-language claims above.
- Reviewed studies (cited in Faraone, 2024): how much of ADHD is explained by genes, from twin and family studies, heritability ~80%.
- Reviewed studies (cited in Faraone, 2024): higher odds of conduct disorder in children with ADHD, odds ratio 10.7 (95% CI 7.7 to 14.8).
- Reviewed studies (cited in Faraone, 2024): higher odds of major depressive disorder in children with ADHD, odds ratio 5.5 (95% CI 3.5 to 8.4).
- Reviewed studies (cited in Faraone, 2024): higher odds of anxiety disorders in children with ADHD, odds ratio 3.0 (95% CI 2.1 to 4.3). What the terms mean:
- Heritability is the share of differences in a trait between people that is linked to genes.
- Odds ratio compares how likely something is in one group versus another; 1 means no difference and higher means more likely.
- 95% CI is the range the true value most likely falls in.
Source: Faraone S, Bellgrove M, Brikell I, et al.. Attention-deficit/hyperactivity disorder. Nature Reviews Disease Primers (2024). doi:10.1038/s41572-024-00495-0